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Duloxetine (Cymbalta), milnacipran (Savella) and pregabalin (Lyrica) are FDA-approved to specifically treat fibromyalgia. Others are used “off-label” – meaning, they’re used by doctors because of observed benefits but are not FDA-approved for fibromyalgia. Some of those drugs are antidepressants but that doesn’t mean that getting a prescription for your fibromyalgia means you are depressed.
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