Fioricet contains a combination of acetaminophen, butalbital, and caffeine Acetaminophen is a pain reliever and fever reducer. Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache. Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.
Fioricet (butalbital, acetaminophen, and caffeine) is a combination pain reliever and muscle relaxant used in the treatment of tension headache and migraine, even any kinds of headache. It is available as a generic prescription. Generic Fioricet is much cheaper than Brand Fioricet but they almost have the same effects and same side effects. The most frequently reported adverse reactions or side effects of fioricet are: drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling.
Common side effects of Fioricet oral:
|Irritation of the Stomach or Intestines||Less Severe|
Infrequent side effects of Fioricet oral:
|Incomplete or Infrequent Bowel Movements||Less Severe|
|Feeling Faint||Less Severe|
|Sensation of Spinning or Whirling||Less Severe|
|Chronic Trouble Sleeping||Less Severe|
|Head Pain||Less Severe|
|Feel Like Throwing Up||Less Severe|
|Throwing Up||Less Severe|
|Easily Angered or Annoyed||Less Severe|
Rare side effects of Fioricet oral:
|Discolored Spots and Small Elevations of the Skin||Severe|
|Acute Pustular Eruptions on Skin||Severe|
|Feeling of Throat Tightness||Severe|
|Acute Liver Failure||Severe|
|Hepatitis caused by Drugs||Severe|
|Inflammation of Skin caused by an Allergy||Severe|
|Toxic Epidermal Necrolysis||Severe|
|Skin Rash with Sloughing||Severe|
|Decreased Calcification or Density of Bone||Severe|
|Loss of Memory||Severe|
|Life Threatening Allergic Reaction||Severe|
|Reaction due to an Allergy||Severe|
|Decreased Blood Platelets||Severe|
|Deficiency of Granulocytes a Type of White Blood Cell||Severe|
|Decreased White Blood Cells||Severe|
|Decreased Neutrophils a Type of White Blood Cell||Severe|
|Taking Habit Forming Drugs||Less Severe|
|Feeling Restless||Less Severe|
|Blind Spot in the Eye||Less Severe|
|Perform Complex Natural behaviors while Asleep||Less Severe|
|Increased Feeling of the Skin||Less Severe|
|Ringing in the Ears||Less Severe|
|Involuntary Quivering||Less Severe|
|Fast Heartbeat||Less Severe|
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:
- fast, pounding, or uneven heartbeat;
- feeling light-headed or short of breath;
- nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
- easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms.
Less serious side effects may include:
- dizziness, confusion or lightheadedness;
- dry mouth;
- nausea, vomiting, stomach pain, loss of appetite;
- feeling anxious or jittery;
- drunk feeling; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Fioricet
Do not use Fioricet if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
You should not use Fioricet if you are allergic to acetaminophen, butalbital, or caffeine, if you have porphyria, or if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.
To make sure Fioricet is safe for you, tell your doctor if you have:
- liver disease, cirrhosis, a history of alcoholism or drug addiction, or if you drink more than 3 alcoholic beverages per day;
- kidney disease;
- asthma, sleep apnea, or other breathing disorder;
- stomach ulcer or bleeding;
- a history of skin rash caused by any medication;
- a history of mental illness or suicidal thoughts; or
- if you use medicine to prevent blood clots.
It is not known whether Fioricet will harm an unborn baby. If you use butalbital while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.